Contact us today +1 425 407 0121 | info@snblusa.com

Regenerative Medicine

FaviconSNBL USA, a premier nonclinical CRO, offers a broad range of regenerative medicine/gene therapy services supported by our scientific team with expertise in stem cell biology, neuroscience, pathology and molecular biology. In addition to extensive experience with a wide variety of stem cell types and gene therapy products, our team can work with you directly to custom design GLP or non-GLP studies specific to your product and ensure that all final protocols are IACUC-approved.

uncommon
Advantages

Experienced program directors in regenerative medicine

Team expertise in stem cell biology, neuroscience, pathology, molecular biology

Comprehensive analytical support of gene therapy studies
Targeted facility upgrades for program expansion
Specialized CNS delivery and sampling techniques
Multiple models available: NHP, canine, minipig, rabbit & rodent

uncommon
Advantages

Experienced program directors in regenerative medicine

Team expertise in stem cell biology, neuroscience, pathology, molecular biology

Comprehensive analytical support of gene therapy studies

Targeted facility upgrades for program expansion

Specialized CNS delivery and sampling techniques

Multiple models available: NHP, canine, minipig, rabbit & rodent

Stem Cell Experience

Human ESC/iPSC
Neural
Hematopoietic
Mesenchymal

Capabilities

Flow cytometry
Specialized necropsy
Histopathology & immunohistochemistry
Apheresis
Myeloablative preconditioning
Bioanalytical method development & validation
ELISA, qPCR, RT-qPCR and western blot analysis

Flow cytometry
Specialized necropsy
Histopathology & immunohistochemistry
Apheresis
Myeloablative preconditioning

Bioanalytical method development & validation

ELISA, qPCR, RT-qPCR and western blot analysis

Study Designs

Biodistribution

Evaluation of the migration, systemic distribution and persistence of the product

Various routes of administration

Biodistribution

Evaluation of the migration, systemic distribution and persistence of the product

Various routes of administration

Safety Assessment

Comprehensive safety studies
Clinical observations, body weight, food consumption
Clinical chemistry, hematology, coagulation

Safety Assessment

Comprehensive safety studies

Clinical observations, body weight, food consumption

Clinical chemistry, hematology, coagulation

Tumorigenicty

Determination of the potential for formation of benign or malignant tumors

Tumorigenicty

Determination of the potential for formation of benign or malignant tumors

Tissues from stem cell product studies examined for:

Reaction at the site of administration
Host immune response
Ectopic tissue formation
Abnormal proliferation

Contact our Regenerative Medicine Experts

Ask questions. We’re here to help.

Contact our Regenerative Medicine Experts

Ask questions. We’re here to help.